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ED148980 DNA

Description:

AGE-RELATED MACULAR DEGENERATION; AMD
AREDS2 DNA FROM WB dbGaP ID AR2_0487

Affected:

Yes

Sex:

Male

Age:

73 YR (At Sampling)

  • Overview
  • Phenotypic Data
  • External Links

Overview

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Repository AREDS2
Quantity 1 µg
Quantitation Method Please see our FAQ
Race White
Ethnicity Not Hispanic/Latino
Relation to Proband proband
Species Homo sapiens
Common Name Human
Remarks 1 µg DNA, not extracted at Coriell, reported Qubit conc=99.5 µg/mL, reported A260/A280=1.9

Phenotypic Data

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AREDS2 Clinical Data
These data are not intended for analysis and should be used only for sample selection purposes. For analyses, the actual Central GA, any GA and NV AMD fields from the fundus grading datasets (AREDS2_RCA and AREDS2_RCF) are available in the AREDS2 dbGaP.
dbGaP Submitter Subject Id AR2_0487
Consent Status GRU - General Research Use
Control No
Age (Yrs) 73
Sex Male
Race White
Ethnicity Not Hispanic or Latino
RE Baseline AMD Severity Scale 7 - AREDS AMD Severity Scale Step 7
RE Final AMD Severity Scale 8 - AREDS AMD Severity Scale Step 8
RE Final Graded Visit Year 5
LE Baseline AMD Severity Scale 7 - AREDS AMD Severity Scale Step 7
LE Final AMD Severity Scale 11b - Neovascular AMD with end-stage disease (e.g., definite disciform scar, or photocoagulation scar), or two or more of the following five characteristics of neovascular AMD: SSR detachment, PED, subretinal/sub-RPE hemorrhage, hard exudate, or fibrous tissue
LE Final Graded Visit Year 5
Data Definition References Evaluating the Validity of the Age-Related Eye Disease Study Grading Scale for Age-Related Macular Degeneration: AREDS2 Report 10 (2016)
doi: 10.1001/jamaophthalmol.2016.2383; PMID: 27442263; PMCID: PMC8371745


The Age-Related Eye Disease Study severity scale for age-related macular degeneration: AREDS Report No. 17 (2005)
doi: 10.1001/archopht.123.11.1484; PMID: 16286610; PMCID: PMC1472813
Other Study References Long-term Outcomes of Adding Lutein/Zeaxanthin and ω-3 Fatty Acids to the AREDS Supplements on Age-Related Macular Degeneration Progression AREDS2 Report 28 (2022)
doi: 10.1001/jamaophthalmol.2022.1640; PMID: 35653117; PMCID: PMC9164119


Age-Related Eye Disease Study 2 Report Number 12 by the Age-Related Eye Disease Study 2 Optos PEripheral RetinA (OPERA) Study Research Group (2016)
doi: 10.1016/j.ophtha.2016.12.004; PMID: 28089680


The Age-Related Eye Disease Study 2 (AREDS2): study design and baseline characteristics (AREDS2 report number 1) (2012)
doi: 10.1016/j.ophtha.2012.05.027; PMID: 22840421; PMCID: PMC3485447

External Links

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dbGaP Link phs002015.v1.p1

Culture Protocols

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Supplement -
Pricing
Commercial:
$200.00USD
Academic &
Non-profit:
$100.00USD
NEI-grantee
$75.00USD
Add to Cart
How to Order
  • MTA / Assurance Form
  • Statement of Research Intent Form

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